Computationally guided organometallic chemistry: preparation of the heptacyclic pyrazine core of ritterazine N.
نویسندگان
چکیده
Diels-Alder cycloaddition of 10 followed by Wittig homologation and intramolecular diene cyclozirconation of the resulting triene under equilibrating conditions led to the tricyclic 6-6-5 ketone 5 with high diastereocontrol. The derived alpha-azido ketone 16 cyclized efficiently to the heptacyclic pyrazine core of ritterazine N.
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 71 7 شماره
صفحات -
تاریخ انتشار 2006